From e681a5085c4eb38683fd611fe700ade2258690f7 Mon Sep 17 00:00:00 2001 From: Charles Plessy Date: Thu, 1 Sep 2022 11:44:51 +0900 Subject: [PATCH] One more chr with an outlying GC content. --- biblio/35387384.mdwn | 10 ++++++++++ tags/chromosome.mdwn | 5 +++++ 2 files changed, 15 insertions(+) create mode 100644 biblio/35387384.mdwn diff --git a/biblio/35387384.mdwn b/biblio/35387384.mdwn new file mode 100644 index 00000000..2417db0f --- /dev/null +++ b/biblio/35387384.mdwn @@ -0,0 +1,10 @@ +[[!meta title="High quality genome assembly of the anhydrobiotic midge provides insights on a single chromosome-based emergence of extreme desiccation tolerance."]] +[[!tag chromosome]] + +Yoshida Y, Shaikhutdinov N, Kozlova O, Itoh M, Tagami M, Murata M, Nishiyori-Sueki H, Kojima-Ishiyama M, Noma S, Cherkasov A, Gazizova G, Nasibullina A, Deviatiiarov R, Shagimardanova E, Ryabova A, Yamaguchi K, Bino T, Shigenobu S, Tokumoto S, Miyata Y, Cornette R, Yamada TG, Funahashi A, Tomita M, Gusev O, Kikawada T. + +NAR Genom Bioinform. 2022 Apr 5;4(2):lqac029. doi:10.1093/nargab/lqac029 + +High quality genome assembly of the anhydrobiotic midge provides insights on a single chromosome-based emergence of extreme desiccation tolerance. + +[[!pmid 35387384 desc="Sleeping chironomid _Polypedilum vanderplanki_. Resists dessication. Its chr4, and the genes it encodes has a lower GC content than the others. Chr4 harbors genes and loci related to resistance to dehydratation. “One element that may have caused the diversity in Chromosome 4 is DNA damage. We have previously observed extensive DNA damage during larvae anhydrobiosis and the induction of Rad51, an activator of double strand break repair during recovery” Discusses that preference for NHEJ might have caused decrease of GC content."]] diff --git a/tags/chromosome.mdwn b/tags/chromosome.mdwn index fa845073..288710cd 100644 --- a/tags/chromosome.mdwn +++ b/tags/chromosome.mdwn @@ -2,9 +2,14 @@ _in progressss_ +## GC content heterogeneity + Two (out of 20) chromosomes in the genome of the unicellular green alga _Ostreococcus tauri_ have a markedly different GC and transposable element content compared to the others. [[Derelle et al., 2003|biblio/16868079]]. +Chr4 in _Polypedilum vanderplanki_ has lower GC content than the others +([[Yoshida et al., 2022|biblio/35387384]]), and it has been speculated that it +could have been caused by DNA damage. [[!inline pages="tagged(chromosome)" limit=0]] -- 2.47.3