From c23a18d05e3317bd35e04bb07593e11d6c5b8cb5 Mon Sep 17 00:00:00 2001 From: Charles Plessy Date: Tue, 29 Aug 2023 08:54:39 +0900 Subject: [PATCH] =?utf8?q?Caf=C3=A9?= MIME-Version: 1.0 Content-Type: text/plain; charset=utf8 Content-Transfer-Encoding: 8bit --- biblio/37407817.mdwn | 22 ++++++++++++++++++++++ tags/cap.mdwn | 3 +++ 2 files changed, 25 insertions(+) create mode 100644 biblio/37407817.mdwn diff --git a/biblio/37407817.mdwn b/biblio/37407817.mdwn new file mode 100644 index 00000000..054c1d2a --- /dev/null +++ b/biblio/37407817.mdwn @@ -0,0 +1,22 @@ +[[!meta title="Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide"]] +[[!tag cap]] + +Sherwood AV, Rivera-Rangel LR, Ryberg LA, Larsen HS, Anker KM, Costa R, Vågbø CB, Jakljevič E, Pham LV, Fernandez-Antunez C, Indrisiunaite G, Podolska-Charlery A, Grothen JER, Langvad NW, Fossat N, Offersgaard A, Al-Chaer A, Nielsen L, Kuśnierczyk A, Sølund C, Weis N, Gottwein JM, Holmbeck K, Bottaro S, Ramirez S, Bukh J, Scheel TKH, Vinther J. Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide. + +Nature. 2023 Jul;619(7971):811-818. doi:10.1038/s41586-023-06301-3. + +Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide. + +[[!pmid 37407817 desc="Arabidopsis thaliana Nudix pyrophosphohydrolase 23 +(AtNUDX23) decapping followed with adapter ligation results in libraries +enriched in HCV(+) and HCV(-) RNAs. 75% of the HCV RNAs are capped and most of +the rest is 5′ triphosphate. FAD capping was not found in “bovine viral +diarrhea virus (BVDV) and the ortho flavivirus tick-borne encephalitis virus +(TBEV), both from the Flaviviridae family, as well as chikungunya virus +(CHIKV), an alphavirus of the Togaviridae family“. “no replication of +JFH1-SGR-Feo was observed upon riboflavin depletion, whereas replication was +rescued by supplementing exogenous riboflavin or FAD” “inclusion of FAD as the +priming nucleotide resulted in efficient de novo initiation of replication and +production of an initiation product consisting of FAD linked to CMP” +“Incubation of 5′-ppp RNA with recombinant NS5B and flavin mononucleotide (FMN) +did not result in 5′-FAD capping”"]] diff --git a/tags/cap.mdwn b/tags/cap.mdwn index 175d7267..4b5f3495 100644 --- a/tags/cap.mdwn +++ b/tags/cap.mdwn @@ -77,6 +77,9 @@ Atypical caps (work in progress) - Mass spectroscopy and molecular biology detected dinucleoside polyphosphate caps in bacteria ([[Hudeček and coll., 2020|biblio/32103016]]). + - Hepatitis C virus RNA is 5′-capped with flavin adenine dinucleotide + ([[Sherwood and coll., 2023|biblio/37407817]]). + Cap physiology (work in progress) --------------------------------- -- 2.47.3