From 75efbe8ab9a23233d2a8533c1bceee04c347fd33 Mon Sep 17 00:00:00 2001 From: Charles Date: Mon, 15 Oct 2018 15:50:38 +0900 Subject: [PATCH] =?utf8?q?Caf=C3=A9?= MIME-Version: 1.0 Content-Type: text/plain; charset=utf8 Content-Transfer-Encoding: 8bit --- tags/Oikopleura.mdwn | 6 ++++-- 1 file changed, 4 insertions(+), 2 deletions(-) diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn index 30589bb9..d8e90b8a 100644 --- a/tags/Oikopleura.mdwn +++ b/tags/Oikopleura.mdwn @@ -65,8 +65,10 @@ Genome 2010|biblio/21097902]]) - Chromatin domains are rarely longer than 7 nucleosomes ([[Navratilova et al., 2017|biblio/28115992]]). - Some 5-methylcytosine was detected by MeDIP-chip by ([[Navratilova et al., 2017|biblio/28115992]]). - - The entire machinery required for performing NHEJ repair of DSB (which is + - The entire machinery required for performing classical NHEJ repair of DSB (which is conserved from yeast to mammals) is undetectable ([[Denoeud et al., 2010|biblio/21097902]]). + - An alternative or microhomology (MH)-driven end joining pathway is active + and triggers microdeletions at the joining site ([[Deng, Henriet and Chourrout, 2018|biblio/30293719]]). - Only a partial mitochondrial genome was reconstituted in [[Denoeud et al., 2010|biblio/21097902]], due to cloning and sequencing difficulties that may have been caused by oligo-dT stretches. A/T-rich codons are more frequent than @@ -147,7 +149,7 @@ Tools ----- - DNAi was used to screen for maternal genes ([[Omotezako et al., 2017|biblio/28281645]]). - + - CRISPR-Cas9 was used to induce genomic microdeletions ([[Deng, Henriet and Chourrout, 2018|biblio/30293719]]). Development ----------- -- 2.47.3