From 5eb48ce6737f68246ebf283a4d9f8667b10e2760 Mon Sep 17 00:00:00 2001 From: Charles Plessy Date: Thu, 22 Mar 2018 14:10:51 +0900 Subject: [PATCH] Some time ago. --- biblio/29472610.mdwn | 10 ++++++++++ 1 file changed, 10 insertions(+) create mode 100644 biblio/29472610.mdwn diff --git a/biblio/29472610.mdwn b/biblio/29472610.mdwn new file mode 100644 index 00000000..f94d51a0 --- /dev/null +++ b/biblio/29472610.mdwn @@ -0,0 +1,10 @@ +[[!meta title="scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells."]] +[[!tag transcriptome single_cell epigenetic methylation]] + +Nat Commun. 2018 Feb 22;9(1):781. doi:10.1038/s41467-018-03149-4 + +Clark SJ, Argelaguet R, Kapourani CA, Stubbs TM, Lee HJ, Alda-Catalinas C, Krueger F, Sanguinetti G, Kelsey G, Marioni JC, Stegle O, Reik W. + +scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells. + +[[!pmid 29472610 desc="GpC methyltransferase need accessibiltiy to the native chromatin. RNA and DNA are split primor amplification. SMART-seq on RNA and bisulfite (scBS) on DNA. Throughput limited by the DNA/RNA separation."]] -- 2.47.3