From 23685f57c90c721c6e47faad9fb248c0f6bfebcf Mon Sep 17 00:00:00 2001 From: Charles Date: Fri, 29 May 2020 14:42:07 +0900 Subject: [PATCH] =?utf8?q?Caf=C3=A9?= MIME-Version: 1.0 Content-Type: text/plain; charset=utf8 Content-Transfer-Encoding: 8bit --- biblio/32424070.mdwn | 10 ++++++++++ tags/centromere.mdwn | 2 ++ 2 files changed, 12 insertions(+) create mode 100644 biblio/32424070.mdwn diff --git a/biblio/32424070.mdwn b/biblio/32424070.mdwn new file mode 100644 index 00000000..46d607d3 --- /dev/null +++ b/biblio/32424070.mdwn @@ -0,0 +1,10 @@ +[[!meta title="Polymorphic Centromere Locations in the Pathogenic Yeast Candida parapsilosis"]] +[[!tag yeast centromere]] + +Ola M, O'Brien CE, Coughlan AY, Ma Q, Donovan PD, Wolfe KH, Butler G. + +Genome Res. 2020 May;30(5):684-696. doi:10.1101/gr.257816.119. + +Polymorphic Centromere Locations in the Pathogenic Yeast Candida parapsilosis + +[[!pmid 32424070 desc="HA epitope introduced into centromeric histone H3 (Cse4) using CRISPR-Cas9 editing. ChIP-seq then identified centromeres. “The species C. parapsilosis is therefore polymorphic for centromere location on two chromosomes. The centromere relocations are associated with a transition from a structured (IR) format to a format with no obvious structure or sequence dependence, within a single species. On Chromosome 5, it is likely that the centromeres on both copies of this chromosome have moved to a new location. It is possible that C. parapsilosis 90-137 is heterozygous at CEN1, with Cse4 at the expected location on one copy of Chromosome 1 and at a new location on the other copy.” “The C. parapsilosis neocentromeres are formed at regions that are transcribed, and transcription is known to facilitate centromere activity in S. cerevisiae”"]] diff --git a/tags/centromere.mdwn b/tags/centromere.mdwn index 8b7d5d35..e24282ed 100644 --- a/tags/centromere.mdwn +++ b/tags/centromere.mdwn @@ -10,5 +10,7 @@ _Work in progress_ coll., 2019|biblio/31306061]]. - Centromere breakage and inactivation in yeast: [[Sankaranarayanan and coll., 2020|biblio/31958060]]. + - Centromere relocation to a transcribed region in yeast, detected by ChIP of + centromeric H3 [[Ola and coll., 2020|biblio/32424070]]. [[!inline pages="tagged(centromere)" limit="0"]] -- 2.47.3