From 087da52f239b10bd3464d29dad4f5a443a980d82 Mon Sep 17 00:00:00 2001 From: Charles Plessy Date: Thu, 11 Nov 2021 13:30:44 +0900 Subject: [PATCH] =?utf8?q?Caf=C3=A9?= MIME-Version: 1.0 Content-Type: text/plain; charset=utf8 Content-Transfer-Encoding: 8bit --- biblio/34593604.mdwn | 10 ++++++++++ 1 file changed, 10 insertions(+) create mode 100644 biblio/34593604.mdwn diff --git a/biblio/34593604.mdwn b/biblio/34593604.mdwn new file mode 100644 index 00000000..e411c73c --- /dev/null +++ b/biblio/34593604.mdwn @@ -0,0 +1,10 @@ +[[!meta title="DNA repair inhibition leads to active export of repetitive sequences to the cytoplasm triggering an inflammatory response."]] +[[!tag repeat repair brain]] + +Song X, Aw JTM, Ma F, Cheung MF, Leung D, Herrup K. + +J Neurosci. 2021 Sep 28:JN-RM-0845-21. doi:10.1523/JNEUROSCI.0845-21.2021. + +DNA repair inhibition leads to active export of repetitive sequences to the cytoplasm triggering an inflammatory response. + +[[!pmid 34593604 desc="Microglial cells accumulate cytoplasmic DNA by damage or inhibition of repair. Blocking DNA export reduces accumulation of cytoplasmic DNA and inflamation. Transcriptionally inactive sequences, AT-rich regions and repeated elements are enriched in the cytoplasmic DNA fraction."]] -- 2.47.3