From: Charles Plessy <plessy@riken.jp>
Date: Thu, 5 Apr 2018 00:40:01 +0000 (+0900)
Subject: Hier.
X-Git-Url: https://source.charles.plessy.org/?a=commitdiff_plain;h=e6db0da9981d24e26845d041451e1c51db5a0a38;p=source.git

Hier.
---

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+[[!meta title="Precise Cas9 targeting enables genomic mutation prevention."]]
+[[!tag CRISPR]]
+
+Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3669-3673 doi:10.1073/pnas.1718148115
+
+Alejandro Chavez, Benjamin W. Pruitt, Marcelle Tuttle, Rebecca S. Shapiro, Ryan J. Cecchi, Jordan Winston, Brian M. Turczyk, Michael Tung, James J. Collins and George M. Church.
+
+Precise Cas9 targeting enables genomic mutation prevention.
+
+[[!pmid 29555762 desc="Destabilising mutations in the guide RNA allow for discrimination of SNPs.  The targetted SNP is not in the host genome at the moment that the prevention system is inserted."]]