From: Charles Plessy <charles.plessy@oist.jp>
Date: Mon, 28 Aug 2023 23:54:39 +0000 (+0900)
Subject: Café
X-Git-Url: https://source.charles.plessy.org/?a=commitdiff_plain;h=c23a18d05e3317bd35e04bb07593e11d6c5b8cb5;p=source--%2F.git

Café
---

diff --git a/biblio/37407817.mdwn b/biblio/37407817.mdwn
new file mode 100644
index 00000000..054c1d2a
--- /dev/null
+++ b/biblio/37407817.mdwn
@@ -0,0 +1,22 @@
+[[!meta title="Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide"]]
+[[!tag cap]]
+
+Sherwood AV, Rivera-Rangel LR, Ryberg LA, Larsen HS, Anker KM, Costa R, Vågbø CB, Jakljevič E, Pham LV, Fernandez-Antunez C, Indrisiunaite G, Podolska-Charlery A, Grothen JER, Langvad NW, Fossat N, Offersgaard A, Al-Chaer A, Nielsen L, Kuśnierczyk A, Sølund C, Weis N, Gottwein JM, Holmbeck K, Bottaro S, Ramirez S, Bukh J, Scheel TKH, Vinther J. Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide. 
+
+Nature. 2023 Jul;619(7971):811-818. doi:10.1038/s41586-023-06301-3.
+
+Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide.
+
+[[!pmid 37407817 desc="Arabidopsis thaliana Nudix pyrophosphohydrolase 23
+(AtNUDX23) decapping followed with adapter ligation results in libraries
+enriched in HCV(+) and HCV(-) RNAs.  75% of the HCV RNAs are capped and most of
+the rest is 5′ triphosphate.  FAD capping was not found in “bovine viral
+diarrhea virus (BVDV) and the ortho flavivirus tick-borne encephalitis virus
+(TBEV), both from the Flaviviridae family, as well as chikungunya virus
+(CHIKV), an alphavirus of the Togaviridae family“.  “no replication of
+JFH1-SGR-Feo was observed upon riboflavin depletion, whereas replication was
+rescued by supplementing exogenous riboflavin or FAD”  “inclusion of FAD as the
+priming nucleotide resulted in efficient de novo initiation of replication and
+production of an initiation product consisting of FAD linked to CMP”
+“Incubation of 5′-ppp RNA with recombinant NS5B and flavin mononucleotide (FMN)
+did not result in 5′-FAD capping”"]]
diff --git a/tags/cap.mdwn b/tags/cap.mdwn
index 175d7267..4b5f3495 100644
--- a/tags/cap.mdwn
+++ b/tags/cap.mdwn
@@ -77,6 +77,9 @@ Atypical caps (work in progress)
  - Mass spectroscopy and molecular biology detected dinucleoside polyphosphate caps
    in bacteria ([[Hudeček and coll., 2020|biblio/32103016]]).
 
+ - Hepatitis C virus RNA is 5′-capped with flavin adenine dinucleotide
+   ([[Sherwood and coll., 2023|biblio/37407817]]).
+
 Cap physiology (work in progress)
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