From: Charles Plessy Date: Thu, 17 Nov 2022 04:52:28 +0000 (+0900) Subject: Fièvre X-Git-Url: https://source.charles.plessy.org/?a=commitdiff_plain;h=98c40858342aad8479606a661a21629af7201693;p=source--%2F.git Fièvre --- diff --git a/biblio/36379955.mdwn b/biblio/36379955.mdwn new file mode 100644 index 00000000..796db0f7 --- /dev/null +++ b/biblio/36379955.mdwn @@ -0,0 +1,10 @@ +[[!meta title="Muscle5: High-accuracy alignment ensembles enable unbiased assessments of sequence homology and phylogeny."]] +[[!tag alignment software]] + +Nat Commun. 2022 Nov 15;13(1):6968. doi:10.1038/s41467-022-34630-w + +Edgar RC. + +Muscle5: High-accuracy alignment ensembles enable unbiased assessments of sequence homology and phylogeny. + +[[!pmid 36379955 desc="Random variations of HMM parameters and guide trees in different replicates to explore systematic biases and remove them by averaging the replicates. “Unlike typical conservation-based metrics, a column with many gaps or with biochemically dissimilar amino acids will be assigned high [confidence] if it is consistently reproduced.”"]]