From: Charles Plessy Date: Fri, 13 Jul 2018 02:31:28 +0000 (+0900) Subject: RA X-Git-Url: https://source.charles.plessy.org/?a=commitdiff_plain;h=98b31c7fc081b2af56d79c9407167c3fad56dd54;p=source.git RA --- diff --git a/biblio/27406791.mdwn b/biblio/27406791.mdwn new file mode 100644 index 00000000..1ac5037d --- /dev/null +++ b/biblio/27406791.mdwn @@ -0,0 +1,10 @@ +[[!meta title="Coelimination and Survival in Gene Network Evolution: Dismantling the RA-Signaling in a Chordate."]] +[[!tag Oikopleura]] + +Martí-Solans J, Belyaeva OV, Torres-Aguila NP, Kedishvili NY, Albalat R, Cañestro C. + +Mol Biol Evol. 2016 Sep;33(9):2401-16. doi:10.1093/molbev/msw118 + +Coelimination and Survival in Gene Network Evolution: Dismantling the RA-Signaling in a Chordate. + +[[!pmid 27406791 desc="Some genes are lost (_Aldh1a_, _Cyp26_, _Rdh10_, _Rdh16_, and _Bco1_) and others show signs of neofunctionalisation (_RdhE2_, _Aldh8a1_). “_O. dioica_ did not contain atRA at concentrations that were likely to play any role in developmental or physiological processes.”"]] diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn index b9deb058..affc1fba 100644 --- a/tags/Oikopleura.mdwn +++ b/tags/Oikopleura.mdwn @@ -136,6 +136,11 @@ Physiology - Adh3 is the only medium-chain alcohol dehydrogenase (MDR-Adh) in _Oikopleura_ (like in other non-vertebrates). Conservation of critical residues and similarity in expression pattern suggest that its metabolic targets are the same as in other species. + - Most members of retinoic acid pathway gene network (biosynthesis, signalling + and degradation) are lost in _O. dioica_. Some of the remaining ones show + signs of neofunctionalisation or specialisation in their ancestral activity in + digestion or chemical defence. ([Martí-Solans et al., 2016|biblio/27406791]) + Phenotypes ----------