From: Charles Plessy <plessy@riken.jp>
Date: Mon, 8 May 2017 07:02:59 +0000 (+0900)
Subject: Café.
X-Git-Url: https://source.charles.plessy.org/?a=commitdiff_plain;h=94ce526cf28a624121b9253727fa4a0b9264ac51;p=source.git

Café.
---

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+[[!meta title="Impact of cytosine methylation on DNA binding specificities of human transcription factors."]]
+[[!tag mC selex transcription_factor epigenetic]]
+
+Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J.
+
+Science. 2017 May 5;356(6337). pii: eaaj2239. doi:10.1126/science.aaj2239
+
+Impact of cytosine methylation on DNA binding specificities of human transcription factors.
+
+[[!pmid 28473536 desc="“Binding of most major classes of transcription factors, including bHLH, bZIP, and ETS, was inhibited by mCpG. In contrast, transcription factors such as homeodomain, POU, and NFAT proteins preferred to bind methylated DNA.”"]]