From: Charles Plessy Date: Mon, 5 Jun 2023 10:55:51 +0000 (+0900) Subject: Science is in the air... X-Git-Url: https://source.charles.plessy.org/?a=commitdiff_plain;h=61202ff9734265e9055efb714aa2aaee82fcab51;p=source.git Science is in the air... --- diff --git a/biblio/26166067.mdwn b/biblio/26166067.mdwn new file mode 100644 index 00000000..4fb52d73 --- /dev/null +++ b/biblio/26166067.mdwn @@ -0,0 +1,15 @@ +[[!meta title="Comparative genomics reveals conserved positioning of essential genomic clusters in highly rearranged Thermococcales chromosomes"]] +[[!tag bacteria variants]] + +Matteo Cossu, Violette Da Cunha, Claire Toffano-Nioche, Patrick Forterre, Jacques Oberto + +Biochimie. 2015 Nov;118:313-21. doi:10.1016/j.biochi.2015.07.008 + +Comparative genomics reveals conserved positioning of essential genomic clusters in highly rearranged Thermococcales chromosomes + +[[!pmid 26166067 desc="“The comparative genomics analysis presented here +confirms the initial observation that Thermococcales chromosomes are highly +rearranged. In these genomes, DNA sequence scrambling has reached such a high +level that commonly observed prokaryotic chromosomal landmarks such as oriC and +terC are no longer readily identifiable by measuring DNA composition +biases.”"]] diff --git a/tags/variants.mdwn b/tags/variants.mdwn index fea90940..c86aa2db 100644 --- a/tags/variants.mdwn +++ b/tags/variants.mdwn @@ -67,7 +67,9 @@ The state of the art in bacterial genomics in 2000 was reviewed by A mixture of X-shaped dot-plot pattern and scrambling was reported by [[Zivanovic and coll. (2002)|biblio/11972326]] in a study of _Pyrococcus_ -genomes. +genomes. Scrambling in _Thermococcales_ appears to be fast enough that +the usual compositional biases on both sides of the origin of replication +do not have time to establish ([[Cossu and coll., 2015|biblio/26166067]]). ### Mechanism