From: Charles Plessy Date: Fri, 31 Jan 2025 05:21:05 +0000 (+0900) Subject: Egg sandwich and café X-Git-Url: https://source.charles.plessy.org/?a=commitdiff_plain;h=473218fd77c33e73bc6cf00baabc5cec024cb1b3;p=source--%2F.git Egg sandwich and café --- diff --git a/biblio/38278805.mdwn b/biblio/38278805.mdwn new file mode 100644 index 00000000..3ce6a14e --- /dev/null +++ b/biblio/38278805.mdwn @@ -0,0 +1,10 @@ +[[!meta title="Large-scale genomic rearrangements boost SCRaMbLE in Saccharomyces cerevisiae."]] +[[!tag yeast synthetic]] + +Cheng L, Zhao S, Li T, Hou S, Luo Z, Xu J, Yu W, Jiang S, Monti M, Schindler D, Zhang W, Hou C, Ma Y, Cai Y, Boeke JD, Dai J. + +Nat Commun. 2024 Jan 26;15(1):770. doi:10.1038/s41467-023-44511-5 + +Large-scale genomic rearrangements boost SCRaMbLE in Saccharomyces cerevisiae. + +[[!pmid 38278805 desc="“SparLox83R, a yeast strain containing 83 loxPsym sites distributed across all 16 chromosomes” “LOH and aneuploidy are frequently detected in SCRaMbLEd heterozygous diploids” “the proportion of rearrangement events was 10-fold higher in haploid than in diploid cells.”"]] diff --git a/tags/synthetic.mdwn b/tags/synthetic.mdwn index 07a6d002..47755312 100644 --- a/tags/synthetic.mdwn +++ b/tags/synthetic.mdwn @@ -14,6 +14,8 @@ Artificial genome scrambling in yeast 2.0 with loxPsym sites: [[Brooks and coll, Artificial 18 kbp random chromosome in yeast: [[Gvozdenov, Barcutean and Struhl, 2023|biblio/37137302]]. +SparLox83R contains 83 loxPsym sites distributed across all 16 chromosomes ([[Cheng and coll., 2024|biblio/38278805]]). + ## Pathway Increasing the copy number of the endogenous aldehyde dehydrogenase Hfd1