From: Charles Plessy Date: Mon, 27 Dec 2021 02:50:50 +0000 (+0900) Subject: yeaset X-Git-Url: https://source.charles.plessy.org/?a=commitdiff_plain;h=4645ccd2a0cc5c72682427151303b61bcbb30ff0;p=setup%2F.git yeaset --- diff --git a/biblio/21819944.mdwn b/biblio/21819944.mdwn new file mode 100644 index 00000000..8c5f03b5 --- /dev/null +++ b/biblio/21819944.mdwn @@ -0,0 +1,10 @@ +[[!meta title="Comparative study on synteny between yeasts and vertebrates."]] +[[!tag yeast synteny]] + +Drillon G, Fischer G. + +C R Biol. 2011 Aug-Sep;334(8-9):629-38. doi:10.1016/j.crvi.2011.05.011 + +Comparative study on synteny between yeasts and vertebrates. + +[[!pmid 21819944 desc="“Synteny blocks were defined as series of neighboring pairs of orthologs separated by less than 5 nonneighboring reciprocal best-hits in the two compared genomes.” “In vertebrates, the number of synteny blocks increases exponentially with increasing divergence time, varying from a very small number of blocks, 43 between human and chimpanzee, to more than 1900 blocks between dog and zebrafish.” “In yeasts, the number of synteny blocks is more restrained, varying from 26 between Candida albicans and C. dubliniensis up to 744 between Debaryomyces hansenii and Pichia pastoris. The number of blocks also exponentially increases along with protein divergence but only between 8 and 36% of divergence. At increasing phylogenetic distances, the number of synteny blocks decreases.” “For both yeast and vertebrate, the average number of shared orthologs per synteny block decreases exponentially with increasing evolutionary distance”"]] diff --git a/tags/synteny.mdwn b/tags/synteny.mdwn index 5ec7e063..4c67537f 100644 --- a/tags/synteny.mdwn +++ b/tags/synteny.mdwn @@ -33,6 +33,13 @@ the past ~5 My. The chinese munjak has undergone much less fusions. In most cases, long-range chromosome structure (Hi-C) is not conserved between theses two species [[Mudd and coll, 2020|biblio/32873878]]. +[[Drillon and Fischer, 2011|biblio/21819944]] “studied synteny conservation +between 18 yeast species and 13 vertebrate species” and “show that +rearrangement rates are on average 3-fold higher in vertebrates than in yeasts, +and are estimated to be of 2 rearrangements/Myr”. They defined synteny as +“series of neighboring pairs of orthologs separated by less than 5 +nonneighboring reciprocal best-hits”. + ### Ancestral karyotpyes - The ancestral mammalian genome has 30 chromosomes ([[Zhou and coll., 2021|biblio/33408411]]).