From: Charles Date: Mon, 2 Nov 2020 06:36:39 +0000 (+0900) Subject: Emphasis and papers. X-Git-Url: https://source.charles.plessy.org/?a=commitdiff_plain;h=3215a00ccf35b0a6d4ac18c39862c8914aaea034;p=source.git Emphasis and papers. --- diff --git a/open-source-biologist.mdwn b/open-source-biologist.mdwn index a7cabb82..dc03f0ad 100644 --- a/open-source-biologist.mdwn +++ b/open-source-biologist.mdwn @@ -41,7 +41,7 @@ for FACS-isolated cells, and one for the Fluidigm C1 platform ([Kouno and coll., 2019](https://pubmed.gov/30664627)). I have complemented my work on CAGE with the development of a gene-centred -technique for detecting promoters, termed Deep-RACE ([Olivarius and coll., +technique for detecting promoters, termed **Deep-RACE** ([Olivarius and coll., 2009](https://pubmed.gov/19317658), [Plessy and coll., 2012](http://dx.doi.org/10.1002/9783527644582.ch4)), which we used to validate our discovery of the pervasive expression of retrotransposons detected by CAGE @@ -63,16 +63,21 @@ demonstrate the expression of haemoglobin in the midbrain ([Biagioli and coll., localisation of RNA in **Purkinje neurons** ([Kratz and coll., 2014](https://pubmed.gov/24904046)), and neurogenesis in the mouse olfactory epithelium using single-cell CAGE and ATAC-seq techniques. In parallel with -this promoter-centric work, I have also explored the huge repertoire of the T -cell antigen receptors. I also applied the nanoCAGE technology to patient -samples infected with the human papillomavirus (HPV) ([Taguchi and coll., +this promoter-centric work, I have also explored the huge repertoire of the **T +cell antigen receptors**. I also applied the nanoCAGE technology to patient +samples infected with the **human papillomavirus** (HPV) ([Taguchi and coll., 2020](https://pubmed.gov/33093512)). I joined OIST in 2018, to study **the genetic structure and population -variations** of an animal plankton, _Oikopleura dioica_, that has a genome -50 time more compact than the human one, which empowers us to sequence -at chromosomal resolution many individual sampled from all over the -World. +variations** of an animal plankton, **_Oikopleura dioica_**, that has a genome +50 time more compact than the human one, which empowers us to sequence at +chromosomal resolution many individual sampled from all over the World. Its +mitochondria use a different genetic code than ours ([Pichon and coll., +2019](https://pubmed.gov/32148763)). We assembled whole-chromosome sequences +for the Okinawan _O. dioica_ population ([Bliznina and coll., +2020](https://doi.org/10.1101/2020.09.11.292656)), which has 3 pairs of +chromosomes ([Liu and coll, 2020](https://f1000research.com/articles/9-780/v1)) +like the other dioceous species. I am also a **Free Software** enthusiast, and contribute to the Debian Med project, by **packaging bioinformatics tools**, which are redistributed in