From: Charles Plessy <charles.plessy@oist.jp>
Date: Mon, 8 May 2023 00:17:00 +0000 (+0900)
Subject: APEX2 / APE2
X-Git-Url: https://source.charles.plessy.org/?a=commitdiff_plain;h=0847223f5a5a872c1a90afb3ac1ca293425cbe7b;p=source%2F.git

APEX2 / APE2
---

diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn
index 475eb22c..3791499b 100644
--- a/tags/Oikopleura.mdwn
+++ b/tags/Oikopleura.mdwn
@@ -276,6 +276,8 @@ Genes and pathways
    ([[Niimura, 2009|biblio/20333175]]).
  - Most members of retinoic acid pathway gene network (biosynthesis, signalling
    and degradation) are lost in _O. dioica_ ([[Martí-Solans et al., 2016|biblio/27406791]]).
+ - APEX2 (encoding for the APE2 protein involved in base excision repair and microhomology
+   mediated end-joining (MMEJ) was not found, but APEX1 was found ([[Denoeud et al., 2010|biblio/21097902]]).
  - The entire machinery required for performing classical NHEJ repair of DSB (which is
    conserved from yeast to mammals) is undetectable ([[Denoeud et al., 2010|biblio/21097902]]).
    An alternative or microhomology (MH)-driven end joining pathway is active