GOC

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+[[!meta title="DNA repeats lead to the accelerated loss of gene order in bacteria."]]
+[[!tag synteny]]
+
+Rocha, Eduardo P C.
+
+Trends Genet. 2003 Nov;19(11):600-3. doi:10.1016/j.tig.2003.09.011
+
+DNA repeats lead to the accelerated loss of gene order in bacteria.
+
+[[!pmid 14585609 desc="Defines a Gene Order Conservation (GOC) number as: “the average number of orthologues for which the consecutive orthologue co-occurs close by in the other genome. It varies between 0 (no co-occurrence) and 1 (complete gene order conservation)”."]]

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@@ -50,4 +50,11 @@ two species [[Mudd and coll, 2020|biblio/32873878]].
 
  - The ancestral amniote has 49 chromosomes ([[Sacerdot and coll., 2018|biblio/30333059]]).
 
+### Computational aspects
+
+ - [[Rocha (2003)|biblio/14585609]] defines a Gene Order Conservation (GOC)
+   number as: “the average number of orthologues for which the consecutive
+   orthologue co-occurs close by in the other genome. It varies between 0 (no
+   co-occurrence) and 1 (complete gene order conservation)”.
+
 [[!inline pages="tagged(synteny)" limit=0]]