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+[[!meta title="Gibbon genome and the fast karyotype evolution of small apes."]]
+[[!tag chromosome synteny evolution]]
+
+Carbone L, Harris RA, Gnerre S, Veeramah KR, Lorente-Galdos B, Huddleston J,
+Meyer TJ, Herrero J, Roos C, Aken B, Anaclerio F, Archidiacono N, Baker C,
+Barrell D, Batzer MA, Beal K, Blancher A, Bohrson CL, Brameier M, Campbell MS,
+Capozzi O, Casola C, Chiatante G, Cree A, Damert A, de Jong PJ, Dumas L,
+Fernandez-Callejo M, Flicek P, Fuchs NV, Gut I, Gut M, Hahn MW,
+Hernandez-Rodriguez J, Hillier LW, Hubley R, Ianc B, Izsvák Z, Jablonski NG,
+Johnstone LM, Karimpour-Fard A, Konkel MK, Kostka D, Lazar NH, Lee SL, Lewis LR, 
+Liu Y, Locke DP, Mallick S, Mendez FL, Muffato M, Nazareth LV, Nevonen KA,
+O'Bleness M, Ochis C, Odom DT, Pollard KS, Quilez J, Reich D, Rocchi M, Schumann 
+GG, Searle S, Sikela JM, Skollar G, Smit A, Sonmez K, ten Hallers B, Terhune E,
+Thomas GW, Ullmer B, Ventura M, Walker JA, Wall JD, Walter L, Ward MC, Wheelan
+SJ, Whelan CW, White S, Wilhelm LJ, Woerner AE, Yandell M, Zhu B, Hammer MF,
+Marques-Bonet T, Eichler EE, Fulton L, Fronick C, Muzny DM, Warren WC, Worley KC,
+Rogers J, Wilson RK, Gibbs RA.
+
+Nature. 2014 Sep 11;513(7517):195-201. doi:10.1038/nature13679
+
+Gibbon genome and the fast karyotype evolution of small apes.
+
+[[!pmid 25209798 desc=""“We identified 96 gibbon–human synteny breakpoints in Nleu1.0.”  “Segmental duplication enrichment was the best predictor of gibbon–human synteny breakpoints,[...] however, breakpoints were also enriched for Alu elements.”  “ The majority of gibbon chromosomal breakpoints bore signatures of non-homology based mechanisms.” “We observed an enrichment of gibbon–human breakpoints in CTCF-binding events.”]]

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 [[!meta title="pages tagged synteny"]]
 
-[[Renschler and coll, (2019)|biblio/31601616]] found 20 synteny breakpoints
+[[Carbone and coll. (2014)|biblio/25209798]] found 96 gibbon–human synteny
+breakpoints (~30 per Gb), associated with segmental duplication or Alu element
+enrichment.  They often bore signatures of non-homology based mechanisms, and
+were enriched near CTCF-binding events.
+
+[[Renschler and coll. (2019)|biblio/31601616]] found 20 synteny breakpoints
 (SB) per Mb on average. “Approximately 75% of SBs stay within the A or B
 compartment”  “Overlaps of TAD boundaries and SB breakpoints in all comparisons
 are highly significant”