for the comparison of multiple Nanopore runs on the same plot, to assess if
read length is satisfactory.
-The Flye assembler ([[Kolmogorov and coll. (2018)|biblio/30936562]]) creates an
+The Flye assembler ([[Kolmogorov and coll., 2018|biblio/30936562]]) creates an
A-Bruijn (assembly) graph from draft contigs using long error-prone reads,
untangles the graph by resolving repeats, and then uses it to refine the
contings and increase their accuracy. (The predecessor of Flye, ABruijn, was
-reported by [[Istace and coll. (2017)|biblio/28369459]] to be able to assemble
+reported by [[Istace and coll. (2017)|biblio/28369459]] to be able to assemble
mitochondrial genomes, unlike Canu and other assemblers.)
After assembly, the contigs can be further polished with Racon ([[Vaser, Sović,
When coverage is too low for efficient reference-free assembly, related
references can be used as a guide. The Ragout software ([[Kolmogorov and
-coll., 2014|biblio/24931998), [[Kolmogorov and coll., 2018|biblio/30341161]])
+coll., 2014|biblio/24931998]]), [[Kolmogorov and coll., 2018|biblio/30341161]])
can take multiple reference genomes to guide the assembly of one target.
Polymorphisms unique to the target genome can be recovered, but chromosome
fusions are typically hard to detect. Compared to version 1, version 2 infers
tools to get the high-quality haplotype assembly based on the reference haploid
assembly_”.
-SALSA (Simple AssembLy ScAffolder, [Ghurye and coll., 2017|biblio/28701198]])
+SALSA (Simple AssembLy ScAffolder, [[Ghurye and coll., 2017|biblio/28701198]])
takes Hi-C data and contigs as input and scaffolds them under the hypothesis
that most contact points are due to local (same-chromosome) proximity. Version
2 of SALSA uses unitigs and the assembly graph as input ([[Ghurye and coll.,