Notochord cell proliferation in the adult.

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+[[!meta title="Continued growth and cell proliferation into adulthood in the notochord of the appendicularian Oikopleura dioica."]]
+[[!tag Oikopleura H3S10p]]
+
+Søviknes AM, Glover JC.
+
+Biol Bull. 2008 Feb;214(1):17-28. doi:10.2307/25066656
+
+Continued growth and cell proliferation into adulthood in the notochord of the appendicularian _Oikopleura dioica_.
+
+[[!pmid 18258772 desc="Actin stained with phalloidin, DNA stained with To-Pro-3, and BrdU stained with antibodies.  Dual H2S10p and BrdU staining in the adult notochord suggest cell proliferation."]]

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+++ b/tags/H3S10p.mdwn
@@ -6,4 +6,8 @@ Dmitrov (2003)|biblio/12917355]] for review.
 Figure 1j of [[Ganot P1, Kallesøe T, Thompson EM (2007)|biblio/17123503]] shows
 H3S10p staining of meiotic chromosomes in π-conformation in mature oocytes.
 
+The monoclonal antibody 9706S used in [[Søviknes and Glover
+(2008)|biblio/18258772]] stains the phosphorylated serine 10 on histone 3.
+Double-staining with BrdU in the notocord suggests adult cell proliferation.
+
 [[!inline pages="tagged(H3S10p)" limit=0]]

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@@ -444,6 +444,7 @@ Development
    Postlethwait (2000)|biblio/10753519]]).
  - Notochord cell precursors express _Brachyury_ like in other chordates
    ([[Bassham and Postlethwait (2000)|biblio/10753519]]).
+ - Adult notochord cells proliferate ([[Søviknes and Glover, 2008|biblio/18258772]).
  - Expression of development genes is retarded by polyunsaturated aldehydes produced
    by diatoms ([[Torres-Águila and coll., 2018|biblio/30272001]]).
  - Epithelial cells divide by mitosis during embryogenesis.  Once the final number