Kafei

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+[[!meta title="Extreme heterochiasmy and high rates of sex-reversed recombination result in large yet homomorphic sex chromosomes in the Emei moustache toad."]]
+[[!tag frog sex variants]]
+
+Xie S, Li J, Chen W, Fong LJM, Huang C, Feng Y, Ai Q, Zhao M, Mank JE, Wu H.
+
+Genome Res. 2025 Jun 2;35(6):1325-1336. doi:10.1101/gr.280161.124
+
+Extreme heterochiasmy and high rates of sex-reversed recombination result in large yet homomorphic sex chromosomes in the Emei moustache toad.
+
+[[!pmid 40274362 desc="        “Population genetic data showed high rates of sex-reversed XY-type females, and recombination between the X and Y Chromosomes in these individuals helps maintain the integrity of sequence and gene expression on the Y Chromosome.”  “Despite this large size and the assumption that inversions catalyze recombination suppression between the X and Y Chromosomes, we found little evidence of XY structural variation.”  “High collinearity and similarity between X and Y haplotypes implicate a pre-existing pattern of low recombination itself, likely predating the origin of Chr 1 as the sex chromosomes, rather than structural variation, in sex chromosome formation.” "]]

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@@ -87,6 +87,10 @@ the same transposon participate in an aberrant transposition event to a new
 site”.  They give an example where the two transposons are identical copies
 on sister chromatids in G2 phase.
 
+[[Xie and coll., 2025|biblio/40274362]] showed that in Emei moustache toad,
+recombination between X and Y chromosomes was low despite the absence of
+large-scale inversions.
+
 ## Indels
 
 Indel-seq ([[Min and coll., 2023|biblio/37402370]]) shows insertions at