Signet.

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+[[!meta title="Negative selection in humans and fruit flies involves synergistic epistasis."]]
+[[!tag genetics not_read]]
+
+Science. 2017 May 5;356(6337):539-542. doi:10.1126/science.aah5238
+
+Sohail M, Vakhrusheva OA, Sul JH, Pulit SL, Francioli LC; Genome of the Netherlands Consortium; Alzheimer’s Disease Neuroimaging Initiative, van den Berg LH, Veldink JH, de Bakker PIW, Bazykin GA, Kondrashov AS, Sunyaev SR.
+
+Negative selection in humans and fruit flies involves synergistic epistasis.
+
+[[!pmid 28473589 desc="'Deleterious LOF mutations are further away from each other in the genome than expected by chance."]]