Oublié je-ne-sais quandÃÃ

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+[[!meta title="Multiscale analysis of the randomization limits of the chromosomal gene organization between Lepidoptera and Diptera."]]
+[[!tag Drosphila synteny]]
+
+Ranz JM, González PM, Su RN, Bedford SJ, Abreu-Goodger C, Markow T.
+
+Proc Biol Sci. 2022 Jan 26;289(1967):20212183. doi:10.1098/rspb.2021.2183
+
+Multiscale analysis of the randomization limits of the chromosomal gene organization between Lepidoptera and Diptera.
+
+[[!pmid 35042416 desc="Uses 5 to 7000 1-to-1 orthologues to study synteny in insects that speciated ~100 My ago.  Uses a definition of microsynteny with no constrains on orientation, where transposition does not interrupt synteny, and where triplets of orthologues do not need to be in the same order.  A repurposed tissue-specificity index identifies ancestral relationships between chromosomes.  Searched for conserved clusters (Hox etc.) by allowing a distance of 250 kbp between genes, regardless the number of interveining genes.  Found that most clusters still exist, but rearranged."]]