Beniimo croissant

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+[[!meta title="Conservation of regulatory elements with highly diverged sequences across large evolutionary distances."]]
+[[!tag synteny]]
+
+Nat Genet. 2025 Jun;57(6):1524-1534. doi: 10.1038/s41588-025-02202-5
+
+Phan MHQ, Zehnder T, Puntieri F, Magg A, Majchrzycka B, Antonović M, Wieler H, Lo BW, Baranasic D, Lenhard B, Müller F, Vingron M, Ibrahim DM.
+
+Conservation of regulatory elements with highly diverged sequences across large evolutionary distances.
+
+[[!pmid 40425826 desc="“Interspecies point projection (IPP) [is] a synteny-based algorithm designed to map corresponding genomic locations in highly diverged genomes”. “We term [...] sequence-diverged orthologs ‘indirectly conserved’ (IC)”"]]

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@@ -127,4 +127,8 @@ Chiton species of very similar morphology can have different karyotypes
  - “Chains” and “nets” of pairwise alignements between two genomes are described
    in [[Kent and coll, 2003|biblio/14500911]].
 
+ - [[Phan and coll., 2025|biblio/40425826]] use syntenic bridge alignments to
+   associate unalignable pairs of sequences in pairs of evolutionary distant
+   species, using an approach they call interspecies point projection (IPP).
+
 [[!inline pages="tagged(synteny)" limit=0]]