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+[[!meta title="Improved DNA-versus-Protein Homology Search for Protein Fossils"]]
+[[!tag bioRxiv LAST repeat]]
+
+Yin Yao, Martin C. Frith
+
+bioRxiv 2021.01.25.428050; doi: https://doi.org/10.1101/2021.01.25.428050
+
+Improved DNA-versus-Protein Homology Search for Protein Fossils
+
+[[!doi 10.1101/2021.01.25.428050 desc="Uses a 64 x 21 substitution matrix and automatically learns the genetic code. Detected fossils of the polinton and DIRS/Ngaro repeat elements in the human genome. 10 times faster than blastx."]]
- `tandem-genotypes` ([[Mitsuhashi and coll., 2019|biblio/30890163]]): detection
of expansion of tandem repeats, after alignment with `last-split`.
+ - LAST can align DNA sequences to protein databases using a 64 x 21 substitution
+ matrix [[Yao and Frith, 2020|biblio/10.1101_2021.01.25.428050]].
+
[[!inline pages="tagged(LAST)" actions="no" limit=0]]