Café

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+[[!meta title="PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions."]]
+[[!tag genome alignment]]
+
+Lin MF, Jungreis I, Kellis M.
+
+Bioinformatics. 2011 Jul 1;27(13):i275-82. doi: 10.1093/bioinformatics/btr209
+
+PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions.
+
+[[!pmid 21685081 desc="Classifies coding and non-coding regions using multiple genome sequence alignments and the fit with separate codon score matrices for coding an non-coding."]]

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@@ -21,4 +21,8 @@ see [[LAST]] for a detailed bibliography.
    an iterative approach where ancestral genomes are reconstituted using 2-5 pairs
    of in- and out-group comparisons, and then progressively aligned to each other.
 
+## Consumers of multiple genome sequence alignments
+
+ - PhyloCSF ([[Lin, Jungreis and Kellis (2011)|biblio/21685081]]).
+
 [[!inline pages="tagged(alignment)" limit=0]]