mesosynteny

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+[[!meta title="A novel mode of chromosomal evolution peculiar to filamentous Ascomycete fungi."]]
+[[!tag yeast synteny]]
+
+Hane JK, Rouxel T, Howlett BJ, Kema GH, Goodwin SB, Oliver RP.
+
+Genome Biol. 2011;12(5):R45. doi:10.1186/gb-2011-12-5-r45
+
+A novel mode of chromosomal evolution peculiar to filamentous Ascomycete fungi.
+
+[[!pmid 21605470 desc="Defines “mesosynteny” as the phenomonon seen when gene order varies at the scale of whole chromosomes, but gene content of homologous chromosomes does not vary much.  Reports that in fungi, mesosynteny is found in filamentous Ascomycetes but not in other clades such as yeast.  Concludes on the possibility that inversions play a role in mesosynteny."]]

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@@ -40,6 +40,11 @@ and are estimated to be of 2 rearrangements/Myr”.  They defined synteny as
 “series of neighboring pairs of orthologs separated by less than 5
 nonneighboring reciprocal best-hits”.
 
+[[Hane and coll, 2011|biblio/21605470]] noted that in filamentous Ascomycetes,
+but not other fungi such as yeast, “genes are conserved within homologous
+chromosomes, but with randomized orders and orientations“ and call that
+phenomenon “mesosynteny”.
+
 ### Ancestral karyotpyes
 
  - The ancestral mammalian genome has 30 chromosomes ([[Zhou and coll., 2021|biblio/33408411]]).