Dans l'avion

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+[[!meta title="Purge Haplotigs: allelic contig reassignment for third-gen diploid genome assemblies."]]
+[[!tag assembly software]]
+
+Roach MJ, Schmidt SA, Borneman AR.
+
+BMC Bioinformatics. 2018 Nov 29;19(1):460. doi:10.1186/s12859-018-2485-7
+
+Purge Haplotigs: allelic contig reassignment for third-gen diploid genome assemblies.
+
+[[!pmid 30497373 desc="Aligns the reads to the draft genome in order to estimate coverage.  A bimodal distribution is expected: the 0.5× peak represents areas where both alleles are present in the assembly."]]

diff --git a/tags/assembly.mdwn b/tags/assembly.mdwn
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--- a/tags/assembly.mdwn
+++ b/tags/assembly.mdwn
@@ -38,6 +38,10 @@ Relase notes of HM2 version 20180603 suggest to use “_HapCUT2 or other phasing
 tools to get the high-quality haplotype assembly based on the reference haploid
 assembly_”.
 
+Purge Haplotigs ([[Roach, Schmidt and Borneman (2018) |biblio/30497373]]) is an
+alternative to HaploMerger that takes read coverage into account when detecting
+potential haplotigs.
+
 SALSA (Simple AssembLy ScAffolder, [[Ghurye and coll., 2017|biblio/28701198]])
 takes Hi-C data and contigs as input and scaffolds them under the hypothesis
 that most contact points are due to local (same-chromosome) proximity.  Version