CAGE

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+[[!meta title="Abundant capped RNAs are derived from mRNA cleavage at 3’UTR G-Quadruplexes"]]
+[[!tag CAGE 3′_UTR]]
+
+Nejc Haberman, Holly Digby, Rupert Faraway, Rebecca Cheung, Andrew M Jobbins, Callum Parr, Kayoko Yasuzawa, Takeya Kasukawa, Chi Wai Yip, Masaki Kato, Hazuki Takahashi, Piero Carninci, Santiago Vernia, Jernej Ule, Christopher R Sibley, Aida Martinez-Sanchez, Boris Lenhard
+
+bioRxiv 2023.04.27.538568; doi:10.1101/2023.04.27.538568
+
+Abundant capped RNAs are derived from mRNA cleavage at 3’UTR G-Quadruplexes
+
+[[!doi 10.1101/2023.04.27.538568  desc="3′ peaks colocalising with a G-rich motif are now explained by AGO2-mediated cleavage of G-quadruplex regions and recapping.  The 3′ fragments and the mRNA did not localise equally in the cell when imaged by in-situ hybridisation."]]