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+[[!meta title="Caenorhabditis elegans DSB-3 reveals conservation and divergence among protein complexes promoting meiotic double-strand breaks."]]
+[[!tag meiosis nematode]]
+
+Hinman AW, Yeh HY, Roelens B, Yamaya K, Woglar A, Bourbon HG, Chi P, Villeneuve AM.
+
+Proc Natl Acad Sci U S A. 2021 Aug 17;118(33):e2109306118. doi:10.1073/pnas.2109306118
+
+_Caenorhabditis elegans+ DSB-3 reveals conservation and divergence among protein complexes promoting meiotic double-strand breaks.
+
+[[!pmid 34389685 desc="DSB-3, likely homologue of Mei4, interacts with DSB-1 and DSB-2 (likely homologues of Rec114).  Together, they are interdependent for localisation to meiotic nuclei and promoting formation of crossovers.  Yeast two-hybrid experiments that DSB-3 binds SPO-11 via DSB-1."]]