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+[[!meta title="Patterning through differential endoreduplication in epithelial organogenesis of the chordate, Oikopleura dioica."]]
+[[!tag Oikopleura cell_cycle]]
+
+Ganot P, Thompson EM.
+
+Patterning through differential endoreduplication in epithelial organogenesis of the chordate, _Oikopleura dioica_.
+
+Dev Biol. 2002 Dec 1;252(1):59-71. doi:10.1006/dbio.2002.0834
+
+[[!pmid 12453460 desc="In the epithelial cells, “endoreduplication begins before tailshift and stops during gamete differentiation.”  “Endocycles are asynchronous within a given field of oikoplastic cells, but the replication pattern is bilaterally symmetrical.”  “In mature animals, final ploidy levels ranged from a low of 34 C in chain of pearl nuclei to 1300 C in giant Eisen nuclei.”  Cells with higher ploidy had shorter gap phases."]]

diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn
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+++ b/tags/Oikopleura.mdwn
@@ -392,6 +392,10 @@ Development
    ([[Bassham and Postlethwait (2000)|biblio/10753519]]).
  - Expression of development genes is retarded by polyunsaturated aldehydes produced
    by diatoms ([[Torres-Águila and coll., 2018|biblio/30272001]]).
+ - Epithelial cells divide by mitosis during embryogenesis.  Once the final number
+   of cells is produce, they grow by endomitosis, with final ploidy ranging between
+   ~30 to ~1300 C. Cells with higher ploidy have shorter gap phases.  Endomitoses
+   stop when gamete differentiation starts.  [[Ganot and Thompson, 2002|biblio/12453460]]
  - Endocycling cells show no polytenisation nor _in loco_ amplifications.  Deep invaginations
    of the nuclear envelopper are shown by simultaneous staining of DNA, RNA and membranes
    ([[Spada and coll., 2007|biblio/17288541]]).