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+[[!meta title="Acid-sensing ion channels emerged over 600 Mya and are conserved throughout the deuterostomes."]]
+[[!tag Oikopleura]]
+
+Proc Natl Acad Sci U S A. 2018 Jul 30. pii: 201806614. doi:10.1073/pnas.1806614115
+
+Lynagh T, Mikhaleva Y, Colding JM, Glover JC, Pless SA.
+
+Acid-sensing ion channels emerged over 600 Mya and are conserved throughout the deuterostomes.
+
+[[!pmid 30061402 desc="O. dioica, like other deuterostomes, has acid-sensing ion channels (ASICs). They are expressed in the nervous system."]]
- _O. dioica_ only has the Dnmt2 methyltransferase, and lacks Dnmt1 and Dnmt3.
- CYP1 family genes and their regulator AhR are not detectable
([[Yadetie et al, 2012|biblio/22300585]]).
-
+ - _O. dioica_, like other deuterostomes, has acid-sensing ion channels (ASICs).
+ They are expressed in the nervous system ([[Lynagh et al., 2018|biblio/30061402]]).
Transcriptome
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