Café

diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn
index 30589bb9438bbd55b5c612d363c136e54f779ff2..d8e90b8af3ffd86151fad1fda5da5baa691bb076 100644 (file)
--- a/tags/Oikopleura.mdwn
+++ b/tags/Oikopleura.mdwn
@@ -65,8 +65,10 @@ Genome
    2010|biblio/21097902]])
  - Chromatin domains are rarely longer than 7 nucleosomes ([[Navratilova et al., 2017|biblio/28115992]]).
  - Some 5-methylcytosine was detected by MeDIP-chip by ([[Navratilova et al., 2017|biblio/28115992]]).
- - The entire machinery required for performing NHEJ repair of DSB (which is
+ - The entire machinery required for performing classical NHEJ repair of DSB (which is
    conserved from yeast to mammals) is undetectable ([[Denoeud et al., 2010|biblio/21097902]]).
+ - An alternative or microhomology (MH)-driven end joining pathway is active
+   and triggers microdeletions at the joining site ([[Deng, Henriet and Chourrout, 2018|biblio/30293719]]).
  - Only a partial mitochondrial genome was reconstituted in [[Denoeud et al.,
    2010|biblio/21097902]], due to cloning and sequencing difficulties that may
    have been caused by oligo-dT stretches.  A/T-rich codons are more frequent than
@@ -147,7 +149,7 @@ Tools
 -----
 
  - DNAi was used to screen for maternal genes ([[Omotezako et al., 2017|biblio/28281645]]).
-
+ - CRISPR-Cas9 was used to induce genomic microdeletions ([[Deng, Henriet and Chourrout, 2018|biblio/30293719]]).
 
 Development
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