Café

diff --git a/biblio/31395756.mdwn b/biblio/31395756.mdwn
new file mode 100644 (file)
index 0000000..f7fe14f
--- /dev/null
+++ b/biblio/31395756.mdwn
@@ -0,0 +1,10 @@
+[[!meta title="A robotic platform for flow synthesis of organic compounds informed by AI planning."]]
+[[!tag automation]]
+
+Coley CW, Thomas DA 3rd, Lummiss JAM, Jaworski JN, Breen CP, Schultz V, Hart T, Fishman JS, Rogers L, Gao H, Hicklin RW, Plehiers PP, Byington J, Piotti JS, Green WH, Hart AJ, Jamison TF, Jensen KF.
+
+Science. 2019 Aug 9;365(6453):eaax1566. doi:10.1126/science.aax1566
+
+A robotic platform for flow synthesis of organic compounds informed by AI planning.
+
+[[!pmid  31395756 desc="An algorithm proposes a synthetic route for a robotic flow chemistry platform, an expect makes practical amendments for safety or efficiency, and the robot assembles the flow platform and runs the synthesis.  Practical challenges remain, such as predicting solubility of the products to avoid clogging the pipes with precipitates."]]

diff --git a/tags/automation.mdwn b/tags/automation.mdwn
index fd4fcf0bb98f7e96a7ef19c9dec55ed597aa7166..3851ef67e0b539e55cc4937ef082df5c653bb26f 100644 (file)
--- a/tags/automation.mdwn
+++ b/tags/automation.mdwn
@@ -6,6 +6,8 @@
 
 Computational planning of the synthesis of complex natural products. ([[Mikulak-Klucznik and coll., 2020|biblio/33049755]]).
 
+Computational planning of compounts for a robotic platform that can assemble an run flow chemistry modules: [[Coley and coll., 2019|biblio/31395756]].
+
 The use of laboratory automation in synthetic biology studied by a sociologist: [[Meckin 2020|biblio/32904024]].
 
 Synthetic sequences that have the same function in a genome need to differ from each other, to prevent from spurious homologous recombinations.  Hossain and coll ([[2020|biblio/32661437]]) optimised an algorithm for producing libraries of "nonrepetitive" elements such as promoters.