Developmental genes.

diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn
index 6fe6f385f2a725f2c4c22b1726e68bdde9433ffa..0aa839430749f5b6fe7d79d297cd103ce451862d 100644 (file)
--- a/tags/Oikopleura.mdwn
+++ b/tags/Oikopleura.mdwn
@@ -66,6 +66,7 @@ Genome
    2008|biblio/19030770]]. The major spliceosome is hypothethised to have evolved
    to become more permissive in order to splice G*-AG sites ([[Denoeud et al., 2010|biblio/21097902]]).
 
+
 Transcriptome
 -------------
 
@@ -90,15 +91,20 @@ Tools
 
  - DNAi was used to screen for maternal genes ([[Omotezako et al., 2017|biblio/28281645]]).
 
+
 Development
 -----------
 
- - The Oikopleura CNS possesses homologs of the vertebrate forebrain,
+ - The _Oikopleura_ CNS possesses homologs of the vertebrate forebrain,
    hindbrain, and spinal cord, but not the midbrain.  No expression of
    _pax2/5/8_ is detected between the _otxa_ + _otxb_ and the _hox1_ territories.
    ([[Cañestro et al., 2005|biblio/16111672]]).
  - The _pum1_ and _vas4_ RNAs show localised expression during development. Prior
    hatching, _pum1_ is found outside the embryo ([[Olsen et al., 2018|biblio/29486709]]).
+ - Duplicated developmental genes were found by [[Denoeud et al., 2010|biblio/21097902]],
+   who noted that it is exceptional in invertebrates, and hypothethise that it may
+   be caused by neofunctionalisation (house production, ...) or by the small size of
+   the genome (doubling the genes would then double the amount of regulatory sequences).
 
 
 Physiology