Evidence for symmetric chromosomal inversions around the replication origin in bacteria.
-[[!pmid 11178265 desc="X-shaped pattern observed in line plots of pairwise comparisons between E. coli and V. cholerae, or Streptococcus or Mycobacterium species."]]
+[[!pmid 11178265 desc="X-shaped pattern observed in line plots of pairwise comparisons between E. coli and V. cholerae, or Streptococcus or Mycobacterium species. The patterns might have been generated by inversions centered on origins and termini of replication."]]
human/mouse comparisons, median length 814.
In bacteria, rearrangements have been reported to generate a X-shaped pattern
-in dot-plots by [[Eisen and coll (2000)|biblio/11178265]].
+in dot-plots by [[Eisen and coll (2000)|biblio/11178265]]. The authors suggest
+that the patterns are generated by inversions centered on origins and termini.
### Mechanism