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+[[!meta title="Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements."]]
+[[!tag sequence_tags ChIP epigenetic]]
+
+Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4813-8 doi:10.1073/pnas.0407069102
+
+Chen J, Sadowski I.
+
+Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements.
+
+[[!pmid 15781865 desc="Ancestor of ChIP-seq. Ditags without a spacer, separated by a 4-cutter (TalI)"]]
15778292 [genome]
2n species covered 1x would be more efficient than n covered 2x for the discovery of conserved elements, but the resulting genome assemblies would be of a much poorer qualities.
-15781865 [tags]
-Not tested on a large scale. Ditags without a spacer, separated by a 4-cutter (TalI)
-
15564293 [misc]
[not read] Normalisations based on uni/multivariate models, rather than substraction of the mean followed by divisoin by sd, are much more effective at detecting covariations.