--- /dev/null
+[[!meta title="Evidence for symmetric chromosomal inversions around the replication origin in bacteria."]]
+[[!tag variants bacteria]]
+
+Eisen JA, Heidelberg JF, White O, Salzberg SL.
+
+Genome Biol. 2000;1(6):RESEARCH0011. doi:10.1186/gb-2000-1-6-research0011
+
+Evidence for symmetric chromosomal inversions around the replication origin in bacteria.
+
+[[!pmid 11178265 desc="X-shaped pattern observed in line plots of pairwise comparisons between E. coli and V. cholerae, or Streptococcus or Mycobacterium species."]]
[[Kent and coll., 2003|biblio/14500911]] reported 2 inversions per Mbp in
human/mouse comparisons, median length 814.
+In bacteria, rearrangements have been reported to generate a X-shaped pattern
+in dot-plots by [[Eisen and coll (2000)|biblio/11178265]].
+
### Mechanism
_Staggered breaks_ ([[Ranz and coll., 2007|bilbio/17550304]]) caused