Café

diff --git a/biblio/30293719.mdwn b/biblio/30293719.mdwn
new file mode 100644 (file)
index 0000000..0038211
--- /dev/null
+++ b/biblio/30293719.mdwn
@@ -0,0 +1,18 @@
+[[!meta title="Prevalence of Mutation-Prone Microhomology-Mediated End Joining in a Chordate Lacking the c-NHEJ DNA Repair Pathway."]]
+[[!tag Oikopleura mutation]]
+
+Deng W, Henriet S, Chourrout D.
+
+Curr Biol. 2018 Sep 27. pii: S0960-9822(18)31132-1. doi:10.1016/j.cub.2018.08.048
+
+Prevalence of Mutation-Prone Microhomology-Mediated End Joining in a Chordate Lacking the c-NHEJ DNA Repair Pathway.
+
+[[!pmid 30293719 desc="In circularisation assays, the ratio between end-joining
+and homologous recombination is similar in O. dioica compared with other
+eukaryotes.  Nevertheless, end-joining is more likely to concatenate than to
+circularise linear plasmids.  The presence of microhomologies trigger
+microdeletions, consistend with the absence of the “classical” end-joining
+pathway.  These microdeletions are much more frequent than in other organisms.
+Comparisons between Norvegian and Japanese strains suggest that the
+microdeletions could be part of the mechansism driving the compaction of O.
+dioica's genome."]]