Histones

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+[[!meta title="Histone variant innovation in a rapidly evolving chordate lineage."]]
+[[!tag Oikopleura histone]]
+
+Histone variant innovation in a rapidly evolving chordate lineage.
+
+BMC Evol Biol. 2011 Jul 15;11:208. doi: 10.1186/1471-2148-11-208.
+
+Moosmann A, Campsteijn C, Jansen PW, Nasrallah C, Raasholm M, Stunnenberg HG, Thompson EM.
+
+[[!pmid 21756361 desc="“47 histone genes (6 H4, 10 H3, 15 H2A, 11 H2B and 5 H1 genes) encoding 31 different histone proteins (2 H4, 6 H3, 11 H2A, 7 H2B and 5 H1) were identified.” “There is no H2AX homolog in O. dioica.” (H2AX is implicated in DNA repair)."]]

diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn
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--- a/tags/Oikopleura.mdwn
+++ b/tags/Oikopleura.mdwn
@@ -138,9 +138,13 @@ Genes and pathways
 
  - ~80 "house proteins" have been identified and more than half lack similarity
    to known proteins ([[Hosp et al., 2012|biblio/22792236]]).
- - “Densitometric analyses of Southern blots yielded estimates of 9–11 H4
-   genes, 11–14 H3 genes, 15–19 H2A genes, 18–20 H2B genes, and 4–7 H1 genes.”
-   [[Chioda, Eskeland and Thompson, 2002|biblio/12446815]]
+
+ - Histones: “Densitometric analyses of Southern blots yielded estimates of
+   9–11 H4 genes, 11–14 H3 genes, 15–19 H2A genes, 18–20 H2B genes, and 4–7 H1
+   genes” ([[Chioda, Eskeland and Thompson, 2002|biblio/12446815]]).  “47 histone
+   genes (6 H4, 10 H3, 15 H2A, 11 H2B and 5 H1 genes) encoding 31 different
+   histone proteins (2 H4, 6 H3, 11 H2A, 7 H2B and 5 H1) were identified”
+   ([[Moosmann and coll., 2011|biblio/21756361]]).
  - 2 cellulose synthase genes, possibly acquired by horizontal gene transfer
    from an actinobacteria ([[Nakashima and coll., 2004|biblio/14740209]]), were
    found by [[Sagane et al. (2010)|biblio/20335363]] and [[Nakashima et al.
@@ -186,6 +190,8 @@ Genes and pathways
    conserved from yeast to mammals) is undetectable ([[Denoeud et al., 2010|biblio/21097902]]).
    An alternative or microhomology (MH)-driven end joining pathway is active
    and triggers microdeletions at the joining site ([[Deng, Henriet and Chourrout, 2018|biblio/30293719]]).
+ - In line with the above, “There is no H2AX homolog in O. dioica.” (H2AX is
+   implicated in DNA repair).  [[Moosmann and coll., 2011|biblio/21756361]]
  - The minor spliceosome could not be found in _Oikopleura_'s genome ([[Martz
    et al., 2008|biblio/19030770]]), [[Denoeud et al., 2010|biblio/21097902]]).
    It is found in _Ciona_ but not in _C. elegans_ ([[Martz et al.,