Earlier report.

diff --git a/biblio/2460825.mdwn b/biblio/2460825.mdwn
index 1e7faae40e9e6ebca0aa015ddd5afb6c057b91a3..997b5cdbdac89fd805c1e1a53a5b6af33e3c1612 100644 (file)
--- a/biblio/2460825.mdwn
+++ b/biblio/2460825.mdwn
@@ -1,6 +1,10 @@
 [[!meta title="Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases."]]
-[[!tag template_switching enzyme]]
-[[!pmid 2460825 desc="‘we cannot exclude the formal possibility that some of these latter
-events, particularly the addition of dCMP by AMV reverse transcriptase, involve the use of coding
-information made available as a result of a transient misalignment of the primer/template
-substrate.’"]]
+[[!tag reverse_transcription enzyme polymerase]]
+
+Nucleic Acids Res. 1988 Oct 25;16(20):9677-86
+
+Clark JM
+
+Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases.
+
+[[!pmid 2460825 desc="Terminal desoxynucleotidyl transferase activity of DNA polymerases, including AMV reverse transcriptase.  Perference for adding As."]]

diff --git a/tags/reverse_transcription.mdwn b/tags/reverse_transcription.mdwn
index 2f7c1952fa3d007e59584d7e700ca453c7dfd0dd..696155c1b500bd019e98107e33d46d38427cc07b 100644 (file)
--- a/tags/reverse_transcription.mdwn
+++ b/tags/reverse_transcription.mdwn
@@ -21,6 +21,9 @@ _(redaction in progress)_
 
 ### Terminal desoxynucleotidyl transferase (TdT) activity
 
+Like other DNA polymerases ([[Clark, 1988|biblio/2460825]]), reverse
+transcriptases have a TdT activity.
+
  - [[Chen & Patton, 2001|biblio/11252793]] reported a TdT activity for MMLV and
    AMV, with a preference for adding As.  For MMLV, activity reduced abruptly
    between 45 and 50 °C.  For AMV, it decreased constantly from 25 to 50 °C.