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+[[!meta title="Evolutionary developmental biology and genomics."]]
+[[!tag Oikopleura epigenetics]]
+
+Nat Rev Genet. 2007 Dec;8(12):932-42 doi:10.1038/nrg2226
+
+Cañestro C, Yokoi H, Postlethwait JH.
+
+Evolutionary developmental biology and genomics.
+
+[[!pmid 18007650 desc="O. dioica only has the Dnmt2 methyltransferase, and lacks Dnmt1 and Dnmt3."]]
- Chromatin domains are rarely longer than 7 nucleosomes ([Navratilova et al., 2017|biblio/28115992]).
- The entire machinery required for performing NHEJ repair of DSB (which is
conserved from yeast to mammals) is undetectable ([[Denoeud et al., 2010|biblio/21097902]]).
- - CYP1 family genes and their regulator AhR are not detectable ([[Yadetie et al, 2012|biblio/22300585]]).
- - ~80 "house proteins" have been identified and more than half lack similarity
- to known proteins ([[Hosp et al., 2012|biblio/22792236]]).
- Only a partial mitochondrial genome was reconstituted in [[Denoeud et al.,
2010|biblio/21097902]], due to cloning and sequencing difficulties that may
have been caused by oligo-dT stretches. A/T-rich codons are more frequent than
“Spots of sequence ultraconservation are almost systematically located
in non coding regions, including introns that are larger than average
in such genes than in others.” ([[Denoeud et al., 2010|biblio/21097902]]).
+
+
+Genes and pathways
+------------------
+
+(See also other sections)
+
+ - ~80 "house proteins" have been identified and more than half lack similarity
+ to known proteins ([[Hosp et al., 2012|biblio/22792236]]).
- _O. dioica_ has multiple CDK1 and Cyclin B paraplogs, some of which are
implicated in oogenesis ([[Feng & Thompson, 2018|biblio/29969934]]).
+ - _O. dioica_ only has the Dnmt2 methyltransferase, and lacks Dnmt1 and Dnmt3.
+ - CYP1 family genes and their regulator AhR are not detectable
+ ([[Yadetie et al, 2012|biblio/22300585]]).
+
Transcriptome
-------------