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+[[!meta title="Evolutionary volatile Cysteines and protein disorder in the fast evolving tunicate Oikopleura dioica."]]
+[[!tag Oikopleura]]
+
+Berná L and Alvarez-Valin F.
+
+Mar Genomics. 2015 Dec;24 Pt 1:47-54. doi:10.1016/j.margen.2015.07.007
+
+Evolutionary volatile Cysteines and protein disorder in the fast evolving tunicate Oikopleura dioica.
+
+[[!pmid 26228312 desc="O. dioica proteins are shorter and proportionally less disordered than in other chordates. Correlation between presence of cysteines (thought to be stabilising) and disorder is lower in O. dioica. Cysteines in ordered domains are also less conserved in O dioica compared to other chordates."]]

diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn
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--- a/tags/Oikopleura.mdwn
+++ b/tags/Oikopleura.mdwn
@@ -115,6 +115,10 @@ Genome
  - Regulatory genes evolve faster.  All aminoacids, including cystein, show reduced
    conservation, suggesting relaxation of functional constraints.  Compared with
    Ciona, 10% of the cysteins are lost ([[Berná and coll., 2012|biblio/22120064]]).
+   Cystein loss happened in both the disordered and ordered protein domains
+   ([[Berná and Alvarez-Valin, 2015|biblio/26228312]]).
+ - Proteins of O. dioica are shorter and contain less disordored domains than proteins
+   from other chrodates ([[Berná and Alvarez-Valin, 2015|biblio/26228312]]).
 
 
 Genes and pathways