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+[[!meta title="Altered miRNA repertoire in the simplified chordate, Oikopleura dioica."]]
+[[!tag Oikopleura miRNA]]
+
+Altered miRNA repertoire in the simplified chordate, _Oikopleura dioica_.
+
+Mol Biol Evol. 2008 Jun;25(6):1067-80. doi:10.1093/molbev/msn060
+
+Fu X, Adamski M, Thompson EM.
+
+[[!pmid desc="miRNA array spotted on N+ membranes.  Confirms the existence of Drosha, DGCR8, Dicer, and 3 AGO proteins. “Five compact clusters containing 15 miRNAs were identified, and the distance between adjacent members was systematically less than 100 bp.” 36% of the miRNAs were long of 22 nucleotides.  “many O. dioica miRNAs were found to be located in the antisense orientation of a protein-coding gene, often opposite the sense strand of an intron.”  “let-7a [...] was not detected during embryogenesis but was observed in the postmetamorphic oikoplastic epithelium.”"]]

diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn
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+++ b/tags/Oikopleura.mdwn
@@ -253,6 +253,8 @@ Genes and pathways
    were found; they might have been created by retrotransposition
    ([[Martí-Solans and coll., 2021|biblio/34179025]]).
  - _Nk4_, _Hand1/2_ and _FoxF_ (heart development, [[Ferrández-Roldán and coll., 2021|biblio/34789899]]).
+ - _O. dioica_ has the miRNA machinery and some miRNAs such as _let-7a_ were detected.  36 % of
+   the miRNAs had a length of 22 nt in [[Fu, Adamski and Thompson, 2008|biblio/18339653]].
 
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