Dans le bus

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+[[!meta title="Genomic basis of recombination suppression in the hybrid between Caenorhabditis briggsae and C. nigoni."]]
+[[!tag nematode]]
+
+Ren X, Li R, Wei X, Bi Y, Ho VWS, Ding Q, Xu Z, Zhang Z, Hsieh CL, Young A, Zeng J, Liu X, Zhao Z.
+
+Nucleic Acids Res. 2018 Feb 16;46(3):1295-1307. doi:10.1093/nar/gkx1277
+
+Genomic basis of recombination suppression in the hybrid between _Caenorhabditis briggsae_ and _C. nigoni_.
+
+[[!pmid 29325078 desc="”the coding sequences of [the] one-to-one orthologs
+exhibited only around a 90% identity, and most of [the] introns and intergenic
+regions were not alignable” “we produced [15,157] one-to-one orthologous gene
+pairs between C. briggsae and C. nigoni.”  “we extracted all of the best hits
+between the two genomes that were >1 kb in size [and] observed over 400
+interchromosomal translocations”  “[we produced] produce homozygous viable
+introgressions representing ∼28% of the C. briggsae genome”   “We observed a
+significantly higher [alignment score] in recombination sites than in genomic
+background”  “Nearly half of the reduced genome in C. briggsae could be
+explained by its lost repeats relative to the C. nigoni genome. These
+differences in genome size and repeat content are expected to create gaps in
+the sequence alignment or make the syntenic sequences not alignable.”"]]

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@@ -65,4 +65,8 @@ Nematode chromosomes have been called “Nigon elements” by [[Tandonnet and co
    of neighboring genes are rearranged in the selfers compared with 15.0% in the
    outcrossers)” ([[Stevens and coll., 2022|biblio/35348662]]).
 
+ - When comparing _C. briggsae_ and _C. nigoni_, most of the introns and
+   intergenic regions are not alignable.  The aligned regions are ~90%
+   identical ([[Ren and coll., 2018|biblio/29325078]]).
+
 [[!inline pages="tagged(nematode)" limit=0]]