Quotes

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@@ -8,3 +8,11 @@ Nat Genet. 2017 Jun;49(6):913-924. doi:10.1038/ng.3847
 Contrasting evolutionary genome dynamics between domesticated and wild yeasts.
 
 [[!pmid 28416820 desc="Yeast subtelomeres accumulate structural variants."]]
+
+“For each subtelomere, we located its proximal boundary on the basis of the sudden loss of synteny conservation and demarcated its distal boundary by the telomere-associated core X and Y′ elements”
+
+“All previously defined essential genes in S. cerevisiae S288C28 fell into the chromosomal cores, whereas all previously described subtelomeric duplication blocks in S288C were fully enclosed in our defined S288C subtelomeres. Furthermore, the genes from our defined subtelomeres showed 36.6-fold higher CNV accumulation than those from the cores”
+
+“subtelomeric one-to-one orthologs also showed significantly higher nonsynonymous-to-synonymous substitution rate ratio (dN/dS) than those from the cores in the S. cerevisiae–S. cerevisiae and S. cerevisiae–S. paradoxus comparisons”
+
+“rapid evolution of subtelomeres can substantially alter the gene repertoire and generate novel recombinants with adaptive potential”