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+[[!meta title="Massive Gene Loss and Function Shuffling in Appendicularians Stretch the Boundaries of Chordate Wnt Family Evolution."]]
+[[!tag Oikopleura]]
+
+Martí-Solans J, Godoy-Marín H, Diaz-Gracia M, Onuma TA, Nishida H, Albalat R, Cañestro C.
+
+Front Cell Dev Biol. 2021 Jun 9;9:700827. doi:10.3389/fcell.2021.700827
+
+Massive Gene Loss and Function Shuffling in Appendicularians Stretch the Boundaries of Chordate Wnt Family Evolution.
+
+[[!pmid 34179025 desc="Localised subcellular expression in the “postplasm” during early embryogenesis. Gene amplification by retrotranscription."]]
+
+”8 _O. dioica_ Wnts belonged to 4 Wnt subfamilies—i.e., Wnt5, Wnt10, Wnt11 (5 sequences) and Wnt16 subfamilies). The results, therefore, show that O. dioica have lost 9 Wnt subfamilies during its evolution. On the other hand, our results revealed that_ O. dioica_ has expanded the Wnt11 subfamily to at least 4 paralogs, named _Odi_Wnt11a_ to _Odi_Wnt11d_.” “Odi_Wnt11b, Odi_Wnt11c, and Odi_Wnt11d, had no introns, pointing to the possibility of a retrotranscriptional origin during the evolution of the appendicularian lineage.”
([[Confalonieri and coll., 2019|biblio/31451549]]).
- Genes related to thyroid functions (_vWFL_, _Nkx2-1_, _FoxE_, _TPO_ and _Duox_)
were studied by [[Onuma and coll., 2020|biblio/34107272]].
+ - 8 Wnt genes were found, belonging to 4 families. Intronless _Wnt11_ genes
+ were found; they might have been created by retrotransposition
+ ([[Martí-Solans and coll., 2021|biblio/34179025]]).
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