--- /dev/null
+[[!meta title="Protection of megabase DNA from shearing."]]
+[[!tag method]]
+
+Nucleic Acids Res. 1995 Oct 11;23(19):3999-4000.
+
+Kovacic RT1, Comai L, Bendich AJ
+
+Protection of megabase DNA from shearing.
+
+[[!pmid 7479050 desc="HCC protects DNA and enhances ligation at 1 mM. HCC is thought to condense DNA, similarly to spermine and spermidine."]]
12448877 [protocols]
Ligating a DNA adaptor 3' to the FScDNA using T4RNA ligase.
-7479050 [protocols]
-HCC protects DNA and enhances ligation at 1 mM. HCC is thought to condense DNA, similarly to spermine and spermidine.
-
4000951 [protocols]
HCC (1 mM) promotes intermolecular ligation. This effect is countered by monovalent cations.