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diff --git a/biblio/12446815.mdwn b/biblio/12446815.mdwn
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+[[!meta title="Histone gene complement, variant expression, and mRNA processing in a urochordate Oikopleura dioica that undergoes extensive polyploidization."]]
+[[!tag Oikopleura histone]]
+
+Chioda M, Eskeland R, Thompson EM.
+
+Mol Biol Evol. 2002 Dec;19(12):2247-60 doi:10.1093/oxfordjournals.molbev.a004048
+
+Histone gene complement, variant expression, and mRNA processing in a urochordate Oikopleura dioica that undergoes extensive polyploidization.
+
+ - [Oikopleura dioica H3.1 gene, H4.1 gene, H1.1 gene, and H2A.1 gene](https://www.ncbi.nlm.nih.gov/nuccore/AJ494848)
+ - [Oikopleura dioica H2A.3 gene for histone h2A.3](https://www.ncbi.nlm.nih.gov/nuccore/AJ494849)
+ - [Oikopleura dioica H3.2 gene for histone h3.2](https://www.ncbi.nlm.nih.gov/nuccore/AJ494850)
+ - [Oikopleura dioica partial H2A.2 gene for histone h2A.2](https://www.ncbi.nlm.nih.gov/nuccore/AJ494851)
+ - [Oikopleura dioica partial H2A.4 gene for histone H2A.4](https://www.ncbi.nlm.nih.gov/nuccore/AJ494852)
+ - [Oikopleura dioica mRNA for histone H2A.1a (H2A.1a gene)](https://www.ncbi.nlm.nih.gov/nuccore/AJ494853)
+ - [Oikopleura dioica partial mRNA for histone h2A.1b (H2a.1b gene)](https://www.ncbi.nlm.nih.gov/nuccore/AJ494854)
+ - [Oikopleura dioica partial mRNA for histone h4 (H4 gene)](https://www.ncbi.nlm.nih.gov/nuccore/AJ494855)
+ - [Oikopleura dioica partial mRNA for histone h1.2 (H1.2 gene)](https://www.ncbi.nlm.nih.gov/nuccore/AJ494856)
+
+[[!pmid 12446815 desc="“Densitometric analyses of Southern blots yielded estimates of 9–11 H4 genes, 11–14 H3 genes, 15–19 H2A genes, 18–20 H2B genes, and 4–7 H1 genes.” “The quintet cluster consisted of a central H1 gene flanked by divergently transcribed H3-H4 and H2A-H2B pairs, an organization found in other organisms such as humans. The quintet cluster is extremely compact, covering only 3.5 kb.” “Both visual inspection and PRATT analysis (Jonassen 1997 ) of the sequences 3′ to the conserved stem-loop revealed no consensus 3′ purine-rich histone downstream element (HDE) that interacts with U7 snRNA in the processing of histone mRNAs. In fact, no consensus sequence or pattern motif of any kind was discovered 3′ of the stem-loop in O. dioica histone gene sequences.”"]]

diff --git a/tags/Oikopleura.mdwn b/tags/Oikopleura.mdwn
index 7bd4a2636123f54415d905ca3625e8b89475bdf1..5c2ac5671f71e82669f7cf879bd29b24fba38a68 100644 (file)
--- a/tags/Oikopleura.mdwn
+++ b/tags/Oikopleura.mdwn
@@ -138,6 +138,9 @@ Genes and pathways
 
  - ~80 "house proteins" have been identified and more than half lack similarity
    to known proteins ([[Hosp et al., 2012|biblio/22792236]]).
+ - “Densitometric analyses of Southern blots yielded estimates of 9–11 H4
+   genes, 11–14 H3 genes, 15–19 H2A genes, 18–20 H2B genes, and 4–7 H1 genes.”
+   [[Chioda, Eskeland and Thompson, 2002|biblio/12446815]]
  - 2 cellulose synthase genes, possibly acquired by horizontal gene transfer
    from an actinobacteria ([[Nakashima and coll., 2004|biblio/14740209]]), were
    found by [[Sagane et al. (2010)|biblio/20335363]] and [[Nakashima et al.
@@ -215,7 +218,8 @@ Transcriptome
    to be older, and among the large introns, the older contain repeat elements less frequently
    than the newer ([[Denoeud et al., 2010|biblio/21097902]]). 
  - 12 developmental stages were studied with tiling arrays by [[Danks et al., 2013|biblio/23185044]].
-
+ - On the histone mRNAs, no purine-rich histone downstream element (HDE) was found
+   by [[Chioda, Eskeland and Thompson in 2002|biblio/12446815]].
 
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