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+[[!meta title="Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing."]]
+[[!tag CAGE promoter motif]]
+
+Nepal C, Hadzhiev Y, Balwierz P, Tarifeño-Saldivia E, Cardenas R, Wragg JW, Suzuki AM, Carninci P, Peers B, Lenhard B, Andersen JB, Müller F.
+
+Nat Commun. 2020 Jan 10;11(1):168. doi:10.1038/s41467-019-13687-0
+
+Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing.
+
+[[!pmid 31924754 desc="In zebrafish, human and drosophila, the majority promoters containing a YC (5′-TOP) TSS motif also carry a YR (PyPu) TSS motif.  In dual YC/YR promoters expression of the two TSS types can be coordinated, but profiling at the zebrafish maternal-zygotic transition also shows cases where they are regulated independently.  The expression of snoRNAs was better correlated with YC-initiation than with YR-initiation."]]